web2py
A web application development stack build with python that runs on most operating systems.
From the web site ->
web2py was inspired by Ruby on Rails and, as Rails, it focuses on rapid development and follows a Model View Controller design. web2py differs from Rails because it is based on Python (thus it is faster and more scalable), because it provides a comprehensive web-based administrative interface (thus there is no need to ever type shell commands unless you wish), includes libraries to handle more protocols (for example XML-RPC and RSS feeds), and can run on the Google App Engine.
web2py was also inspired by Django and, as Django, it has the ability to generate forms from database tables and it includes an extensive set of validators. web2py differs from Django because it is more compact, easier to learn and does not have any project-level configuration files.
web2py is less verbose than Java-based frameworks and its syntax is much cleaner than PHP-based frameworks. This makes applications simpler to developer, easier to read and maintain.
Here is a features comparison of web2py vs other popular web frameworks...
